Using the blood typing chart above, who has the b antigen on their red blood cells?

Using the blood typing chart above, who has the b antigen on their red blood cells?

How do you determine a patient's blood type?

You need to know the patient’s blood type in order to make safe blood transfusions. Primarily you try to give the same blood type in a blood transfusion as the patient has got. From Tutorial 1 you know that the blood type notation indicates what antigens there are on the surface of the red blood cells. So, to determine blood type, you need to find out which antigens are present. You can work that out by mixing the patient’s blood with three different reagents containing either of the three antibodies: A, B or Rh.

Using the blood typing chart above, who has the b antigen on their red blood cells?

Test tubes containing three different reagents with either A, B or Rh antibodies. The antibodies attach to antigens on the patient's red blood cells if they match.

Blood typing procedure:

1. Mix!

First mix the patient's blood with three different reagents including either of the three different antibodies, A, B or Rh antibodies!

Using the blood typing chart above, who has the b antigen on their red blood cells?


2. Look for agglutination!

Then you take a look at what has happened. In which mixtures has clumping, or agglutination, occurred? The agglutination indicates that the blood has reacted with a certain antibody and is therefore not compatible with blood containing that kind of antibody. If the blood does not agglutinate, it indicates that the blood does not have the antigens binding the special antibody in the reagent.

Using the blood typing chart above, who has the b antigen on their red blood cells?


3. Figure out the ABO blood group!

Start by taking a look at the test tubes containing A and B antibodies. Has the blood agglutinated in either of these two tubes?

Using the blood typing chart above, who has the b antigen on their red blood cells?

No agglutination in test tube A, indicates that the patient's red blood cells do not have A antigens.
Agglutination in the tube containing B antibodies indicates that the patients' red blood cells have got B antigens, thus belongs to blood group B.


4. Figure out the Rh blood group!

Now have a look at the test tube containing Rh antibodies! Has the blood agglutinated or not?

Using the blood typing chart above, who has the b antigen on their red blood cells?

No agglutination indicates that the patient's red blood cells don't have Rh antigens, thus the blood is Rh-.


5. Figure out the blood type!

Now that you know which antigens are in the patient's blood, you can figure out the blood type!
Since agglutination only occured in the test tube containing B antibodies, the blood got B antigens but no A or Rh antigens. Thus the blood type is B Rh- .

Using the blood typing chart above, who has the b antigen on their red blood cells?


Test yourself!

Can you determine the blood type?

Using the blood typing chart above, who has the b antigen on their red blood cells?

Agglutination in all three test tubes indicates that all three antigens are present in the blood: A, B and Rh. Accordingly, the blood type is AB Rh+.

Can you determine the blood type?

Using the blood typing chart above, who has the b antigen on their red blood cells?

Agglutination in the test tubes contaning A antibodies and B antibodies. Accordingly, the blood type is AB Rh-.

Can you determine the blood type?

Using the blood typing chart above, who has the b antigen on their red blood cells?

Agglutination in the test tube with Rh antibodies indicates that the blood has got Rh antigens but no A nor B antigens.
The blood type is O Rh+.


What has happened when the blood agglutinates?

The blood will agglutinate if the antigens in the patient's blood match the antibodies in the test tube. A antibodies attach to A antigens - they match like a lock and key - and thus form a clump of red blood cells. In the same way B antibodies attach to B antigens and Rh antibodies to Rh antigens. In the test tubes where agglutination has occured, the patient's red blood cells have been linked together, like bunches of grapes, instead of floating around one by one .


Disclaimer:
The fact that people with Rh- blood do not naturally have Rh antibodies in the blood plasma (as one can have A or B antibodies, for instance) is not taken into consideration in this game. In reality a person with Rh- blood can develop Rh antibodies in the blood plasma if he or she receives blood from a person with Rh+ blood. The received blood cells with Rh antigens can trigger the production of Rh antibodies in an individual with Rh- blood. In the game one has to pretend that all patients with Rh- blood type has received Rh+ blood in previous blood transfusions.

Also, the antibodies are here referred to as A antibodies, B antibodies and Rh antibodies. These are also commonly referred to as anti A antibodies, anti B antibodies, and anti Rh antibodies.

To cite this page
MLA style: "The Blood Typing Game - Tutorial 2: How do you get the blood type?". Nobelprize.org. Nobel Prize Outreach AB 2022.

What blood type has B antigens on its red blood cells?

blood group B – has B antigens with anti-A antibodies in the plasma. blood group O – has no antigens, but both anti-A and anti-B antibodies in the plasma. blood group AB – has both A and B antigens, but no antibodies.

Who described the A and B antigens in blood?

Human Blood: ABO Blood Types. group. They were discovered in 1900 and 1901 at the University of Vienna by Karl Landsteiner in the process of trying to learn why blood transfusions sometimes cause death and at other times save a patient. In 1930, he belatedly received the Nobel Prize for his discovery of blood types.

What antigens are present on B+?

b. Type B+ blood has the B antigen as well as the Rh antigen which makes it B+ on the red blood cell. Type B blood contains anti-A antibodies in the plasma.

Why a person with blood group A has antibody B?

The immune system forms antibodies against whichever ABO blood group antigens are not found on the individual's RBCs. Thus, a group A individual will have anti-B antibodies and a group B individual will have anti-A antibodies.