How many grams of dextrose are required to prepare 4000 mL of a 5% solution
Calculating the amount of solute needed for a specific solution is often required in the histology laboratory. The following ratio can be used: Show % desired/100 mL = g or mL needed/volume desired Preparation of a 1% acid alcohol solution is needed for the decolorization step of the Ziehl-Nielsen method. A liter of the solution is made routinely with concentrated HCl and 70% alcohol. How many milliliters of concentrated HCl are needed to make 1 liter of the 1% acid alcohol solution? (Remember, 1 L = 1000 mL) X = 10 mL concentrated HCl The histologist needs to prepare 500 mL of a 29% ferric chloride solution. Calculate the amount of solute needed. X = 145 g ferric chloride A 0.55% solution of potassium metabisulfite is needed for the periodic acid-Schiff (PAS) stain technique. The histotechnician needs to make 400 mL of this percent solution or 4 times the amount of this 0.55% solution of potassium metabisulfite. 4 X 0.55 g = 2.2 g is needed to make 400 mL of the 0.55% solution. Take 1 tablet by mouth 4 times a day for 2 days and then take 1 tablet by mouth 2 times a day for 5 days. i tab po qid x2d then i tab po bid x5d Instill 3 drops in the left eye every 4 hours around the clock. Apply the cream freely to the affected area every morning and at bedtime. Take 3 capsules by mouth every morning, take two capsules by mouth with food every evening. iii cap po qam and ii cap po c food qpm Instill 1 drop in each eye every 2 hours for 3 days then instill 1 drop in each eye every 6 hours for 2 weeks. i gtt ou q2h x3d then i gtt ou q6h x2wk Give 2 tablespoonfuls by mouth every 6 hours. From the following formula, calculate the quantities required to make 180 mL of benzyl benzoate lotion. Benzyl Benzoate 250 mL 45 mL Benzyl Benzoate 0.9 mL Triethanolamine 3.6 mL Oleic Acid Purified Water qs 180 mL A time-release cold capsule contains the following ingredients. Calculate, in grams, the amount of each ingredient required to manufacture 100,000 capsules. Phenindamine 24 mg 2400 g Phenindamine 400 g Chlorpheniramine 5000 g Pseudoephedrine From the following formula, calculate the quantity of each ingredient required to make 1500 g of powder. Calcium Carbonate 5 parts 115.4 g Magnesium Oxide 577 g Calcium Carbonate 461.5 g Sodium Bicarbonate 346.1 g Bismuth Subcarbonate A narcotic analgesic tablet contains 5 mg of hydrocodone and 500 mg of aspirin. How many grams of each ingredient are needed to prepare 1000 tablets? 5 g hydrocodone 500 g aspirin From the following formula, calculate the quantity of each ingredient required to prepare 10 pints of lotion. Hexachlorophene 0.1 g 3311 g Isopropyl Alcohol 23.65 g Cetyl Alcohol 4.73 g Hexachlorophene Purified Water qs 4730 mL An estradiol transdermal system contains in each skin patch 4 mg of estradiol and 0.3 mL of alcohol. How many grams of estradiol and how many liters of alcohol would be required to manufacture a half-million patches? 2000 g estradiol 150 L alcohol Each milliliter of otic solution contains the following ingredients. Calculate the amount of each ingredient needed to manufacture one thousand 10 mL containers of the product. Antipyrine 54 mg 540 g antipyrine 140 g benzocaine Dehydrated Glycerin ad 10 L An antacid tablet contains 80 mg of aluminum hydroxide and 20 mg of magnesium trisilicate. How many kilograms of each ingredient are required to manufacture 250,000 bottles of the product, each containing 100 tablets? 2000 kg Al(OH)3 500 kg Mg2Si3O8 From the following formula, calculate the quantities required to make 5 lb of hydrophilic ointment. Methylparaben 0.25 g 0.57 g methylparaben 0.34 g propylparaben 22.7 g sodium lauryl sulfate 272.4 g propylene glycol 567.5 g stearyl alcohol 567.5 g white petrolatum Purified water ad 5 lb. = 2270 g A physician prescribes tetracycline suspension for a patient who is to take 2 teaspoonfuls four times a day for 4 days, then 1 teaspoonful four times a day for 2 days. How many milliliters of the suspension should be dispensed to provide the quantity for the prescribed dosage regimen? A patient has been instructed to take 15 mL of alumina and magnesium oral suspension every other hour for four doses daily. How many days will two 12 fl. oz bottles of the suspension last? Lugol’s Solution contains 5 g of iodine per 100 mL. The usual dose is 0.3 mL three times per day. How many milligrams of iodine are represented in the daily dose of the solution? How many milliliters of an injection containing 20 mg of gentamicin in each 2 mL should be used in filling a medication order calling for 2.5 mg of gentamicin to be administered intramuscularly? Cyclosporine is an immunosuppressive agent administered before and after organ transplantation at a single daily dose of 15 mg/kg. How many milliliters of a 50 mL bottle containing 100 mg of cyclosporine per milliliter would be administered to a 140 lb kidney transplant patient? Rx: Erythromycin Estolate 400 mg/5 mL If the dose of erythromycin is given as 40 mg/kg per day: a. What would be the proper dose of the medication in the Signa if the prescription is for a 44 lb child? b. How many days will the medication last? A 25 lb child is to receive 4 mg of phenytoin per kilogram of body weight daily as an anticonvulsant. How many milliliters of pediatric phenytoin suspension containing 30 mg per 5 mL should the child receive? If the pediatric dose of dactinomycin is 15 mcg/kg/day X 5 days, how many micrograms should be administered to a 40 lb child over the course of treatment? A medication order calls for tobramycin, 1mg/kg of body weight, to be administered by IM injection to a patient weighing 220 lbs. Tobramycin is available in a vial containing 80 mg per 2 mL. How many milliliters of the injection should the patient receive? How many grams of fluouracil will a 154 lb patient receive in 5 successive days at a dosage rate of 12 mg/kg/day? If a pharmacist counted 40 drops of a medication in filling a graduated cylinder to the 2.5 mL mark, how many drops per milliliter did the dropper deliver? It takes approximately 4 g of ointment to cover an adult patient’s leg. If the physician prescribes an ointment for a patient with total leg eczema to be applied twice a day for 1 week, which of the following product sizes should be dispensed: 15 g, 30 g, 60g? 56 g needed → dispense 60 g A solution contains 660 mg of sodium fluoride per 120 mL and has a dose of 10 drops. If the dispensing dropper delivers 25 drops/mL, how many milligrams of sodium fluoride are contained in each dose? Rx: Amoxicillin 400 mg/5 mL a. What size bottle, in milliliters, would you administer for a 10 day supply? b. What is the total amount of amoxicillin, in grams, the patient will receive in those 10 days? Rx: Acetaminophen 160 mg/5 mL According to the directions, what is the maximum amount of acetaminophen the patient can take in a day? Ampicillin syrup (125 mg/teaspoonful) How many milliliters of this syrup will the patient take all together? Ephedrine sulfate syrup 60 mL Sig: tsp I qid How many days will this quantity of medication last the patient? A pharmacist measured 35 drops of a medicated solution while filling a graduated cylinder to the 5 ml mark. How many drops per milliliter did the dropper deliver? The pediatric dose of a drug is 200 mg/m2. What is the dose for the child whose body surface area is 0.8 m2? The dose of a drug is 15 mg/m2, twice a day, for 1 week. How many milligrams of the drug should the patient take altogether in the course of treatment? Assume that the patient is an average adult (1.73 m2). Ephedrine sulfate syrup 60mL Sig: 2 tsp tid How many days will this prescription last the patient? Penicillin V suspension 240mL Sig: 400,000 units tid How many days will this prescription last the patient? Sodium pentobarbital 0.09 g Sig: 10 mg of sod. pentobarb. h.s. If the dropper dispensed with the product delivers 2 mL in 48 drops, how many drops would contain 10 mg of sodium pentobarbital? A child weighing 30 lb needs an anticonvulsant in a dose of 5 mg/kg daily. How many milliliters of a pediatric suspension of the drug, containing 20 mg/mL should the child receive? The pediatric dosage of digoxin is based on age and weight. Recommended doses are: full term newborn 20 – 30 μg/kg, 1- 24 months 30 - 50 μg/kg, 2 – 5 years 25 – 35 μg/kg. Calculate the dosage range for: a) A 20 month old baby weighing 16 lb. b) A 3 year old child weighing 55 lb. a) Range = 218 – 364 μg b) Range = 625 – 875 μg A physician orders 5 mg of ampicillin sodium to be added to each milliliter of a 100 mL bag of D5W for intravenous injection. a) How many milligrams of ampicillin sodium should be added? b) If the dose of ampicillin sodium is 20 mg/kg and the 100 mL bag is the daily dose, how many pounds does the patient weigh? A 13 year old, 110 lb child is prescribed minocycline 4 mg/kg/day for 1 month for acne treatment. The daily dose is to be divided into two equal doses. The pharmacist carries 50 and 100 mg capsules. What strength, quantity, and directions should be selected? strength: Minocycline 100 mg quantity: #60 directions: Take one capsule by mouth twice daily for 1 month Potassium Iodide Solution 10% (w/v) Sig. Five drops in water as directed. How many grams each of potassium iodide and ephedrine sulfate should be used in preparing the prescription? 1.5 g potassium iodide. 0.45 g ephedrine sulfate. If a pharmacist dissolves 8 capsules, each containing 250 mg of clindamycin HCl, into a sufficient amount of astringent liquid to make 120 mL of solution, what is the percentage strength (w/v) of clindamycin HCl in the prescription? An injection contains 50 mg of pentobarbital sodium in each milliliter of solution. What is the percentage strength (w/v) of the solution? A pharmacist adds 10 mL of a 20% (w/v) solution of potassium iodide to 500 mL of D5W for parental infusion. What is the percentage strength of potassium iodide in the infusion solution? A liniment contains 15% (v/v) of methyl salicylate. How many milliliters of the liniment can be made from 1 pint of methyl salicylate? A pharmacist incorporates 6 g of coal tar into 120 g of a 5% coal tar ointment. Calculate the percentage (w/w) of coal tar in the finished product. Express each of the following concentrations as a ratio strength: A) 2 mg of active ingredient in 2 mL of solution A) 1:1000 b) 1:18182 c) 1:125 d) 1:500 Hepatitis B Immune Globulin is preserved with 1:10,000 (w/v) of thimerosal. If the dose of the injection is 0.06 mL/kg of body weight, how many micrograms of thimerosal would be contained in the dose for a 150 lb patient? If a liquid vitamin preparation contains 0.16 mcg of vitamin B12 per 5 mL, what is the ratio strength of the preparation? What is the percent concentration of cholesterol in a patient’s blood serum if the cholesterol level is determined to be 260 mg%? How many grams of sodium fluoride should be added to 100,000 liters of drinking water containing 0.6 ppm of sodium fluoride to provide a recommended concentration of 1.75 ppm? How much of a 10% potassium chloride stock solution are needed to prepare 1 gallon of a 1:500 TPN? 76 mL 10% w/v KCl solution You are directed to prepare 5 liters of a 1:25000 (w/v) solution of potassium permanganate. If the potassium permanganate is available only in the form of tablets, each tablet containing 200 mg, how many tablets should be used in preparing the solution? If 1 g of a drug is dissolved in 2.5 mL of glycerin, specific gravity 1.25, what is the percentage strength (w/w) of the drug in the resultant solution? If a commercially available insulin preparation contains 1 ppm of proinsulin, how many micrograms of proinsulin would be contained in a 10 mL vial of insulin? If 250 mL of a 1:800 solution are diluted to 1000 mL, what will be the ratio strength? How many milliliters of water must be added to 250 ml of a 25% (w/v) stock solution of sodium chloride to prepare a 0.9% (w/v) sodium chloride solution? How many milliliters of water should be added to 2500 mL of 83% (v/v) alcohol to prepare 50% (v/v) alcohol? How many milliliters of 95% (w/w) sulfuric acid having a specific gravity of 1.82 should be used in preparing 2 liters of 10% (w/v) acid? In using isoproterenol HCl solution (1:5000), 1 mL of the solution is diluted to 10 mL with sodium chloride injection before intravenous administration. What is the percentage concentration (w/v) of the diluted solution? How many grams of zinc oxide should be added to 3400 g of a 10% zinc oxide ointment to prepare a product containing 15% of zinc oxide? A vaginal douche powder concentrate contains 2% (w/w) of active ingredient. What would be the percentage concentration (w/v) of the resultant solution after a 5 g packet of powder is dissolved in enough water to make 1 quart of solution? What is the percentage of alcohol in a mixture containing 1500 mL of witch hazel (14% alcohol), 2000 mL of glycerin, and 5000 mL of 50 % alcohol? In what proportion should 95% alcohol be mixed with 30% alcohol to make 70% alcohol? 8 parts 95% alcohol to 5 parts 95% alcohol A solution of benzalkomium chloride is available in a concentration of 1:750. How many milliliters of purified water should be added to 30 mL of the solution to prepare a 1:5000 benzalkonium chloride solution for use as a wet dressing? How many milliliters of 50% (w/v) dextrose solution and how many milliliters of 5% (w/v) dextrose solution are required to prepare 4500 mL of a 10% (w/v) solution? 4000 mL 5% dextrose 500 mL 50% dextrose How many milliliters each of 2% iodine tincture and 7% strong iodine tincture should be used in preparing 1 gallon of a tincture containing 3.5% iodine? 1135.5 mL strong 2649.5 mL weak How many milliliters of 28% (w/w) strong ammonia solution having a specific gravity of 0.89 should be used in preparing 2000 mL of 10% (w/w) ammonia solution with a specific gravity of 0.96? 770.5 mL of 28% (w/w) ammonia Rx: Benzalkonium Chloride Solution 240 mL Make a solution such that 10 mL diluted to a liter equals 1:5000 solution How many milliliters of a 17% solution of benzalkonium chloride should be used in preparing the prescription? 28.2 mL 17% stock BC solution How much silver nitrate should be used in preparing 50 ml of a solution such that 5 ml diluted to 500 ml will yield a 1:1000 solution? How many milliliters of water should be added to 375 ml of a solution containing 0.5 g of benzalkonium chloride to make a 1:5000 solution? How many milliliters of 85% (w/w) phosphoric acid having a specific gravity of 1.71 should be used in preparing 1 gallon of ¼% (w/v) phosphoric acid solution to be used for bladder irrigation? If 250 mL of a 1:800 (v/v) solution are diluted to 1000 ml, what will be the ratio strength (v/v)? Aluminum acetate topical solution contains 5% (w/v) of aluminum acetate. When 100 ml are diluted to a liter, what will be the ratio strength (w/v)? If a 0.067% (w/v) methylbenzethonium chloride lotion is diluted with an equal volume of water, what will be the ratio strength (w/v) of the dilution? If 150 ml of a 17% (w/v) concentrate of benzalkonium chloride are diluted to 5 gallons, what will be the ratio strength (w/v) of the dilution? How many milliliters of a 1:50 (w/v) boric acid solution can be prepared from 500 ml of 5% (w/v) boric acid solution? How many milliliters of water must be added to 250 ml of a 25% (w/v) stock solution of sodium chloride to prepare a 0.9% (w/v) sodium chloride solution? How many milliliters of 1:50 (w/v) stock solution of a chemical should be used to prepare 1 liter of a 1:4000 (w/v) solution? A certain product contains benzalkonium chloride in a concentration of 1:5000 (w/v). How many milliliters of a 17% solution of benzalkonium chloride should be used in preparing 4 liters of the product? How many milliliters of water for injection must be added to 10 liters of a 50% (w/v) dextrose injection to reduce the concentration to 30% (w/v)? Menthol 0.1% Label: Menthol and Hexachlorophene Lotion. How many milliliters of a 5% (w/v) solution of menthol in alcohol should be used to obtain the amount of menthol needed in preparing the lotion? How many milliliters of a solution containing 0.275 mg of histamine phosphate per milliliter should be used in preparing 15 ml of a 1:10000 histamine phosphate solution? A physician prescribes an ophthalmic suspension to contain 100 mg of cortisone acetate in 8 ml of normal saline solution. The pharmacist has on hand 2.5% suspension of cortisone acetate in normal saline solution. How many milliliters of this and how many milliliters or normal saline should be used in preparing the prescribed suspension? How many milliliters of water should be added to 100 ml of a 1:125 (w/v) solution to make a solution such that 25 ml diluted to 100 ml will yield a 1:4000 dilution? Zephiran Chloride Solution (17% w/v) 50 ml Sig. One (1) tsp. diluted to a pint with water for topical use. Calculate the ratio strength of zephiran chloride in the dilution. How many milliliters of water should be mixed with 1200 g of 65% (w/w) alcohol to make 45% (w/w) alcohol? A 1:750 (w/v) solution of benzalkonium chloride diluted with purified water in a ratio of 3 parts of the benzalkonium solution and 77 parts of purified water is recommended for bladder and urethral irrigation. What is the ratio strength of benzalkonium chloride in the final solution? How many grams of zinc oxide should be added to 3400 g of 10% zinc oxide ointment to prepare a product containing 15% of zinc oxide? Zinc Oxide 1.5 Sig. Apply to affected areas. How much zinc oxide should be added to the product to make an ointment containing 10% of zinc oxide? If one tablespoonful of a 0.2% (w/v) solution of phenylmercuric acetate is diluted to 1 quart with water, what would be the percentage concentration (w/v) of the resulting solution? How many milligrams of sodium fluoride are needed to prepare 100 ml of a sodium fluoride stock solution such that a solution containing 2 ppm of sodium fluoride results when 0.5 ml is diluted to 250 ml with water? A pharmacist mixes 200 g of 10% ichthammol ointment, 450 g of 5% ichthammol ointment, and 1000 g of petrolatum (diluent). What is the percentage of ichthammol in the finished product? In what proportion should 95% alcohol be mixed with 30% alcohol to make 70% alcohol? In what proportion should 30% and 1.5% hydrogen peroxide solutions be mixed to prepare a 3% hydrogen peroxide solution. How many milliliters of 2.5% (w/v) thiamylal sodium solution and how many milliters of 0.9% (w/v) sodium chloride injection should be used to prepare 500 ml of a 0.3% (w/v) thiamylal sodium solution? A vial of kanamycin sulfate injection contains 500 mg per 2 ml. If 1.6 ml of the injection are diluted to 200 ml with sodium chloride injection, how many milliliters of the dilution should be administered daily to a child weighing 22 lb if the daily dose is 15 mg/kg of body weight? Ringer’s Solution Formula: How much of each ingredient is necessary to make 90 mL of Ringer’s solution? 0.774 g NaCl 0.027 g KCl 0.0297 g CaCl2 SWFI ad 1000 mL becomes ad 90 mL If a source of drinking water contains 1.5 ppm of fluoride, how many micrograms of fluoride are present in half pint of water? How much 20% sulfathiazole ointment should be added to 200 g of 6% sulfathiazole ointment to make an ointment of 10% strength? What is the percentage of alcohol (v/v) in the following prescription? Witch Hazel (contains 15% alcohol, v/v) 20 mL A patient is to receive 45 mg of a drug. How many milliliters of a 1:20 (w/v) solution of the drug should be used? How many milliliters of absolute alcohol (100%) must be used to make 240 mL of a 10% w/v solution of a drug? (SG absolute alcohol = 0.798; SG 10% solution of drug in absolute alcohol = 0.851) How many grams of 1% hydrocortisone cream must be mixed with 0.5% hydrocortisone cream if one wishes to prepare 60 g of a 0.8% w/w preparation? A prescription calls for the dispensing of a 4% Pilocar solution with the directions of “ gtt i OU TID” How many mg of pilocarpine hydrochloride is being used per day? Assume the dropper is calibrated to deliver 20 drops to the mL. A medication order reads “Aclovate Oint 0.05% 15 g – dilute to 0.02% with white pet and apply to hands t.i.d.” How many grams of white petrolatum should the pharmacist use? How many chloramphenicol capsules, each containing 250 mg, are needed to provide 25 mg per kg per day for 7 days for a person weighing 200 lb? How many grams of aspirin should be used to prepare 1.255 kg of the powder? ASA 6 parts The blood of a reckless driver contains 0.1% (w/v) alcohol. Express the concentration of alcohol in parts per million. Syrup is an 85% w/v solution of sucrose in water. It has a density of 1.313 g/mL. How many milliliters of water should be used to make 125 mL of syrup? How many gram of drug are required to make 120 mL of 25% solution?Weight of the drug = 30g.
What is percentage strength?Strength in percentage means how many gH2O2 present per 100mL. ∵M⇒1 and mol.wt.of H2O2=34. ∴34gH2O2 present per litre of solution or 3.
What is the percent strength of a 1 25 weight volume solution?Expert-Verified Answer
Hence the required answer is 5%.
What are the different types of percentage preparations?There are two types of percentage solutions commonly used in histology:. Percentage weight by volume (w/v). Percentage volume by volume (v/v). |